Abstract

Regenerative medicine uses the biological and medical knowledge on how the cells and tissue regenerate and evolve in order to develop novel therapies. Health conditions such as ageing, obesity and cancer lead to an impaired regeneration ability. Exercise, diet choices and sleeping pattern have significant impacts on regeneration biology via diverse pathways including reducing the inflammatory and oxidative components. Thus, exercise, diet and sleeping management can be optimized towards therapeutic applications in regenerative medicine. It could allow to prevent degeneration, optimize the biological regeneration and also provide adjuvants for regenerative medicine.

Highlights

  • Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations

  • Regenerative medicine comes as a branch that aims to understand the regenerative pathways and degenerative processes, both in biology and physiology, to develop methodologies and approaches aiming to correct regeneration-related health challenges and the impaired functions [20] or at least limit the impacts of the variables that can impair regeneration

  • Beside the various adjuvant used in regenerative medicine, mainly pharmacological [41,42,43] or bioengineering [28,44], we aim to highlight the importance of lifestyle and how it impacts regeneration

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Summary

Introduction

Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations. Regeneration processes might be impaired or disturbed in various status including degenerative diseases [11,12,13], cancer [14], obesity [15], ageing [16,17], diabetes mellitus [18] and cholestatic liver [19].

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