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Abstract
The application of PSMA theranostic pairs in the glioblastoma multiform (GBM) has gained attention recently due to reports of PSMA radiotracer uptake in these tumors. The presented case is a 42-year-old man who had a known case of GBM with no response to standard-of-care therapy. However, 6 doses of 100-150 mCi 177 Lu-PSMA-617 therapy with short intervals of 4-5 weeks revealed excellent response on both MRI and 99m Tc-HYNIC-PSMA-11 scintigraphy. Though more dedicated studies are warranted, this case highlighted the potential efficacy of the 177 Lu-PSMA therapy in recurrent refractory GBM.
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