Abstract

Conversion disorder is defined as a disorder with one or more neurological symptoms that accompany psychological conflict, suggesting a physical disorder. It has been shown that patients with conversion disorder have an imbalance in the autonomic nervous system. There are only a limited number of studies that have examined how conversion disorder is related with surface ECG parameters. The present study aimed to investigate the effects of conversion disorder on the surface ECG parameters of patients with conversion disorder admitted to the emergency department. This cross-sectional case-control study included 98 patients who were admitted to the emergency department and diagnosed with conversion disorder and 56 healthy volunteers. All patients underwent 12-derivation ECG. PR interval, P wave dispersion, duration of QRS complex, QT interval, QTc interval, frontal QRS-T angle values were calculated for all individuals. When compared with the control group, the conversion disorder group revealed a significant difference in terms of PWD [60 (40-80) vs. 40 (40-60) P = 0.01], QT [385 (364-410) vs. 378 (354-394), P = 0.048], QTc [420 (405-430) vs. 406 (397-429), P = 0.039], and frontal QRS-T angle [25 (15-33) vs. 20 (8-35), P = 0.018]. In the multivariate linear regression analysis, conversion disorder was found to be an independent predictor for both PWD (β = 0.196, P = 0.014) and frontal QRS-T angle (β = 0.258, P = 0.011). This study is the first to show that conversion disorder significantly increases QT, QTc, P wave dispersion, and frontal QRS-T angle.

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