Abstract

•Continued refinement of this optical imaging technology may lead to improved ability to accurately determine optical margins, facilitate the sparing of uninvolved normal tissue, and find application to novel technological platforms, such as robotic surgery. Figure 1. High Resolution Microendoscope (HRME). The device consists of a fiber-optic bundle which can deliver high resolution narrow field images of tissue morphology. The image is magnified by a microscope objective. Surface staining with a nuclear dye is required to display the morphology of the epithelial nuclei.

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