Abstract
It’s an evolution of its own kind that a technology changed the interface of biology in such a short expanse of time. Merely a decade ago, scientists reported that the CRISPR-Cas (clustered regularly interspaced short Palindromic repeats-CRISPR associated) system is the part of bacteria and archea’s adaptive immune system which helps in withstanding the attack against invading viruses by acquiring genetic records of invaders to facilitate robust interference upon reinfection. In this Review, we discuss the evolution of CRISPR along the time and recent advances in understanding the vivid mechanism by which Cas proteins respond to foreign nucleic acids and how these systems have been harnessed for precise genome manipulation in plants. With the advancement in this technology, it will become easier to genetically modify the plants for crop improvement.
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