Abstract
BackgroundPhylogeographic reconstructions serve as a basis to understand the spread and evolution of pathogens. Visualization of these reconstructions often lead to complex graphical representations which are difficult to interpret.ResultWe present EvoLaps, a user-friendly web interface to visualize phylogeographic reconstructions based on the analysis of latitude/longitude coordinates with various clustering levels. EvoLaps also produces transition diagrams that provide concise and easy to interpret summaries of phylogeographic reconstructions.ConclusionThe main contribution of EvoLaps is to assemble known numerical and graphical methods/tools into a user-friendly interface dedicated to the visualization and edition of evolutionary scenarios based on continuous phylogeographic reconstructions. EvoLaps is freely usable at www.evolaps.org.
Highlights
Phylogeographic reconstructions serve as a basis to understand the spread and evolution of pathogens
We present EvoLaps, a web-based interface dedicated to the visualization and interpretation of phylogeographic reconstructions based on latitude/longitude coordinates
Thanks to the continuous latitude/longitude coordinates associated to a dynamic clustering process, EvoLaps facilitates the search of phylogeographic patterns based on various aggregation levels of locations
Summary
Phylogeographic reconstructions serve as a basis to understand the spread and evolution of pathogens. The geographic map displays the spatial distribution of samples corresponding to the tips of the phylogenetic tree, the clusters of samples defined by the user during the analysis and the resulting phylogeographic The transition diagram A transition is defined as an inferred migration across a pair of geographical clusters between subsequent nodes of the tree in a top-down reading, from the root to the tips in a recursive process (Fig. 4a).
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