Abstract

Intracytoplasmic sperm injection (ICSI) has become the treatment of choice in male infertility due to extreme oligozoospermia. Initially, the technique was limited to the selection and injection of motile spermatozoa with normal morphology; although it has now been shown that spermatozoa with abnormal morphology can also be used successfully.1 We describe a patient referred for ICSI who presented with phenotypically abnormal sperm and we show that in this patient the disturbed spermatogenesis was associated with chromosome abnormalities and abnormal meiosis.

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