Abstract
Tobacco has multiple effects on the hypothalamic-pituitary-thyroid axis and the functioning of the thyroid gland. The adverse mechanisms of smoke exposure include alteration of thyroid hormone synthesis, binding, transport, storage and clearance, thereby resulting in changes in the circulating hormone concentrations. This study was designed to analyze the effect of smoking on thyroid profile, measuring serum TSH, total T3 and total T4 levels in active and passive smokers. The results revealed that both active and passive smokers had highly significant decreased serum total T3 and T4 levels along with substantially increased serum TSH levels in comparison to non-smokers (p < 0.001). However, the variation of hormone status between the both case groups was less statistically significant (p < 0.05), indicating the deleterious nature of tobacco smoke on the activity of thyroid, irrespective of its nature and origin.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Clinical Biochemistry and Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
