Evaluation of the survival of fish in acid environment under the action of ursodeoxycholic acid

Abstract

Currently, there is a sufficient amount of data on agricultural activities, including livestock, animal husbandry and fish farming, which can affect the physico-chemical and biological characteristics of freshwater lakes. However, the consequences of infection, contamination by agricultural activities, on the microbial ecosystem have been unclear.Most toxins are hepatotoxic, so the hepatobiliary system is quite common in fish of all species. Depending on the degree of toxicity of the poison, the severity of the manifestation can manifest itself in the form of massive necrosis of hepatocytes with obvious acute liver failure, and in the form of chronic intoxication with a gradual increase in degenerative processes in the liver.To assess the effectiveness of medicinal products for fish, a first test in the laboratory of the toxicity of pharmaceutical substances that are introduced into the reference preparation is necessary. So, because of diseases - hepatoprotectors is ursodeoxycholic acid (UDCA), which can be of two types - synthetic and extraction. Regardless of its nature, the drug has a place in its pharmacokinetic activity in both veterinary medicine and medicine.At the moment, aqua and mariculture has a colossal dose in modern drugs for pharmacocorrection of pathological non-infectious etiology, which have complexity and a universal integral pharmacological response. However, the discovery of the area of discovery of medicinal compositions occurs due to the non-standard habitat of natural resources compared to classical ones.Research in this area involves the use of new methodological approaches to the design of functional pharmaceutical substances.