Abstract
PurposeThe aim of this study was to evaluate the association between changes in the type of Modic change (MC) and newly developed MCs and low back symptoms.MethodsThis retrospective study includes all the patients suffering from low back pain who has at least two magnetic resonance studies between 2013 and 2016. Patients with MC in at least one vertebra in magnetic resonance imaging (MRI) images were included in the study. The patients who have periods of two MRIs less than six months were excluded.ResultsA total of 129 patients were included in the study and 774 vertebrae were evaluated. At the time of the first admission, MC was observed in 283 out of the 774 vertebrae (37%), whereas in the second admission, MC was observed in 343 of 774 (43%) vertebrae. New MCs were observed in 59 vertebrae. Two patients showed complete resolution of MC in the second admission. It was observed that patients with type 1 change were more associated with pain than other types (p=0.001).ConclusionIn our retrospective case-control study, we have found that MCs can transform into different types or disappear completely over time. A significant positive correlation was found between the presence of MC type 1 changes in the visual analog scale(VAS).
Highlights
It has been suggested that Modic changes (MCs) are a specific reason for low back pain (LBP) [13]
In our retrospective case-control study, we have found that MCs can transform into different types or disappear completely over time
MCs have been determined by magnetic resonance imaging (MRI) since 1988 (Modic et al).; based on histological studies, they are divided into three types [4]
Summary
It has been suggested that Modic changes (MCs) are a specific reason for low back pain (LBP) [13]. It has started to be a subject that attracts attention. MCs have been determined by magnetic resonance imaging (MRI) since 1988 (Modic et al).; based on histological studies, they are divided into three types [4]. A type I MC shows a signal reduction in T1-weighted (T1w) MRI and a signal increase in T2-weighted (T2w) MRI, and, histologically, reflects inflammatory changes in the vertebral endplates [4]. A type II MC T1w and T2w show both signal increase and represent a more stable phase of degenerative disc disease but has the potential to transform into another type. A type III MC shows decreased signal intensity in both
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