Evaluation of the effectiveness of non-invasive methods of compressive microvibration and ablative sensory microvibration on local areas with excess fat deposits in volunteers of different age groups

Abstract

The aim of the study was the apparatus of compressive microvibration “Endospheres Therapy® Body” (Registration certificate RZN 2016/3863 of 29 December 2017) used in women with mild to moderate edematous fibrosclerosis (panniculopathy) of peri- and post-menopausal age. The purpose of the project is to evaluate the effectiveness of the non-invasive technique of compressive microvibration in volunteers of different age groups. The basis for the work is the agreement No. 002/2022-n between the GBUZ MO MONIKI named after M.F. Vladimirsky and ItalConsult, LLC of 01.03.2022. The main tasks were: form 3 cohort groups of volunteers in accordance with the criteria agreed with the Customer (mild or moderate edematous fibrosclerosis, as panniculopathy), aged 30 to 44 years old, 45 to 54 years old and 55-65 years old; ensure that all participants receive a course on procedures (12 procedures every other day) regularly and correctly; evaluate the effectiveness of the non-invasive method of compressive microvibration on local areas of excess fat deposits in volunteers of different age groups through subjective testing (with a questionnaire), objective results of laboratory tests (blood test with hormone levels) and instrumental studies (ultrasound examination of the skin of fat trap zones, in abdomen and thighs) and assessment of the microcirculation system. Hypothesis: compressive microvibration generated by the manipulator-cylinder, consisting of 50 spheres of hypoallergenic silicone that generates low-frequency vibrations, makes it possible to activate microcirculation, stimulate lymphatic drainage, increase muscle tone and improve skin trophism. For all study results, mean values (Mean), standard deviations (Std.Dev.), minimum (Minimum), maximum (Maximum) values, and SD confidence of all results were obtained. The difference between the mean values and the variation coefficients was tested using a two-sample Student’s t-test (considering the distribution’s normality). Our results have convincingly demonstrated the effectiveness of the Endospheres Therapy® procedures for treating cellulite, with the effect maintained for at least 60 days after the course of therapy. Instrumental studies confirmed a pronounced improvement in the skin’s condition, microcirculation, cellular metabolism activation, hypoxia reduction and tissue perfusion improvement. Endospheres Therapy® procedures are safe and effective in treating cellulite in the long term without side effects. Patients noted a high degree of satisfaction with the Endospheres Therapy® course, which indicates the quality of the procedures and the level of specialists.