Evaluation of the cardioprotection efficiency in the treatment of patients with acute myocardial infarction and stable angina pectoris by means of digital processing of ECG (digitalization) with subsequent expert assesment

Abstract

The aim of the work is to investigate the influence of cardiocytoprotection on heart rate variability (HRV) in the treatment of patients with acute Q wave myocardial infarction and stable angina pectoris by digital processing of the ECG and its digitization with a subsequent expert assessment.Material and methods. 124 patients with acute Q-MІ and SAP admitted to regional clinical cardiology center of Chernivtsi during the period 2017-18 were examined. The treatment was held in accordance with the unified records of the Ministry of Healthcare of Ukraine with the evaluating of effectiveness of the implementation of metabolic therapy by using medications Tivortin, Tivorel, Korvityn and Tiotryzolin in comparison with Amiodarone and Bisoprolol in the conditions of the acute test with the registration of the second derivations of the standard ECG for 30 s by using electrocardiograph «Easy ECG MonitorPrince180B» («HealForce» PRC) before using the drugs which were examined and at the height of their effect on patients with Q-IM in comparison with the SAP group.Results. During the research with integrated analysis of impacts of cardiocytoprotection therapy in patients with the Q-IM, in contrast to the SAP group, it was found that arginine chloride reduces the rate of SDNN and activates a sympathetic contour, but the positive is the reduction of the duration and dispersion of QT interval in these patients after using it, arginine chloride and quercetin also reduce the variance of ST segment when MI, and therefore reduce the risk of ischemia and does not indicate the increase of the risk of arrhythmic death, indicated antiarrhythmic direction of the indicator of the maximum rate of differential T wave on the background of using of Corvityn and Tivortin, which is more showed in the case with Tivortin. The possibility of effective quantitative evaluation of the electrocardiogram by digital processing (digitization) by using its own security software «Smart ECG» (certificate of registration of copyright N73687 from 05.09.2017 g.) in the selected groups of patients was proved.Conclusion. Early diagnostic and timely prescription of adequate therapy with inclusion of Bisoprolol, Amiodarone, and medicines with metabolic focus allow us to achieve rapid clinical effect and to prevent the progression of the main pathological process and the development of complications.