EVALUATION OF SERUM LIPID PROFILE IN PATIENTS OF CORONARY ARTERY DISEASE

Abstract

Background: Coronary heart disease (CHD) or cardiovascular diseases are recognized to be one of the most important reasons of morbidity and mortality and imposes tremendously heavy socioeconomic burden worldwide. There are varieties of risk factors in the literature which increases the incidence of CHD such as hyperlipidemia. By the year 2020, World Health Organization (WHO) is predicting more than 11.1 million deaths from CHD. Coronary heart disease occurs when cholesterol accumulates on the artery walls, creating plaques. Reduced blood ow occurs when one or more of these arteries become partially or completely blocked. The four primary coronary arteries are located on the surface of the heart are: right, left main coronary artery, left circumex artery and left anterior descending artery. Material and Methods: The present study was done on 100 patients with acute or severe coronary heart diseases. Serum levels of total cholesterol, HDLcholesterol, LDLcholesterol, and triglycerides were examined by using biochemical kits. Results: The Total Serum Cholesterol to High density lipoprotein-Cholesterol and Low density lipoprotein- Cholesterol to High density lipoprotein-Cholesterol ratios also were signicantly higher in cases than in controls, whereas the rise in Triglycerides to High Density Lipoprotein-Cholesterol ratio was not found to be signicant. Conclusion: It was found that the total cholesterol, HDLcholesterol, LDLcholesterol and triglycerides concentrations were signicantly higher in coronary heart disease patients.