Evaluation of Serum Lipid Profile in Hypertensive Patients at Mirpur Khas, Sindh, Pakistan

Abstract

Aim: To assess the lipid profile of hypertensive patients. Study Design: Evaluation-based study. Place and duration of study: Department of Medicine, Muhammad Medical College Hospital, Mirpurkhas, Sindh, Pakistan for a period of one year from 1stJuly 2020 to 30thJune 2021. Methodology: Three hundred and fifty-three hypertensive patients were enrolled in the study based on Rao-soft formula. Only those hypertensive patients who had confirmed diagnosis of hypertension were enrolled. The patients were requested for fasting to take the blood sample. Results: 64.87% were males and 35.1% were females. 39.6% patients were above 60 years old and highest range values for systolic blood pressure 201-220mmHg. The majority of the patients 26.34% showed 91-100 mm Hg. The 11.05% of the patients were prescribed with the Atenolol, 7.08% of patients were prescribed with another beta blocker medication Propranolol. The majority of patients were prescribed with Rosuvastatin as antilipidemic drugs however the least majority i.e. 11.61 were prescribed with Simvastatin.The 16.9% patients showed HDL40mg/dL, higher LDL<100mg/dL, total glycerides<150mg/dL, total cholesterol<200mg/dL HDL30-39mg/dL, LDL100-150mg/dL, total glycerides150-200 mg/dL, total cholesterol200-250mg/dL among 31.73% of the patients. The 28.9% of the patients showed the pattern HDL20-29mg/dL. Conclusion: The dyslipidemia associated with the hypertension and hypertensive patients. The irregular values and alteration of in the serum cholesterol and total cholesterol levels of lipid profile proves the association of lipid profile with the elevated systolic blood pressure levels. The total cholesterol, LDL and HDL can be controlled with an appropriate controlling of high blood pressures, thus preventing the cardiovascular diseases and cardiovascular diseases. Key words: Lipid, Hypertension, Assess