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Abstract
BackgroundTo evaluate the ocular pulse amplitude (OPA) in patients with chronic non-arteritic anterior ischaemic optic neuropathy (NAION).MethodsThis cross-sectional study comprised a study group of 30 eyes from 30 patients with NAION and a control group of 31 eyes from 31 age and gender-matched healthy subjects. Bilateral OPA was measured with dynamic contour tonometry (DCT) and was compared between the study and control groups.ResultsNo statistically significant difference was found between the study and control groups in terms of hypertension, diabetes mellitus, ischaemic heart disease and hyperlipidemia. The mean intraocular pressure (IOP) measured with Goldmann Applanation Tonometry and DCT in the study and control groups was not statistically different (p1 = 0.094, p2 = 0.240). The mean OPA in the study group and the control group were 2.01 ± 0.69 mmHg and 1.97 ± 0.68 mmHg (p = 0.839).ConclusionNo significant difference was determined in the OPA levels of eyes with NAION at the chronic stage and eyes in the control group.
Highlights
To evaluate the ocular pulse amplitude (OPA) in patients with chronic non-arteritic anterior ischaemic optic neuropathy (NAION)
Anterior ischaemic optic neuropathy (AION) is a consequence of ischaemic injury to the anterior section of the optic nerve, which is an area of circulation fed by the posterior ciliary arteries
In patients with NAION, there is reduced blood flow in the short posterior ciliary arteries (SPCAs) [7], there has been no histopathological evidence of thrombosis of the SPCAs in the very few cases that have been studied [8, 9]
Summary
To evaluate the ocular pulse amplitude (OPA) in patients with chronic non-arteritic anterior ischaemic optic neuropathy (NAION). Anterior ischaemic optic neuropathy (AION) is a consequence of ischaemic injury to the anterior section of the optic nerve, which is an area of circulation fed by the posterior ciliary arteries. NAION constitutes 95% of all AION and in those aged >50 years, is the most frequent cause of acute optic neuropathy. In patients with NAION, there is reduced blood flow in the short posterior ciliary arteries (SPCAs) [7], there has been no histopathological evidence of thrombosis of the SPCAs in the very few cases that have been studied [8, 9]. It is believed that the condition is caused by generalized hypoperfusion in some cases and by occlusion of disc or laminar capillaries in others
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