Abstract
Interpenetrating polymer network of cross-linked blend microspheres for controlled release of Acebutolol HClP. Ramakrishna, B. Mallikarjuna, A. Chandra Babu, P. Sudhakar, K. Chowdoji Rao, M.C.S. Subha
Highlights
Chitosan is a cationic linear polysaccharide containing randomly dispersed β-(1-4)-linked D-glucosamine and N-acetylD-glucosamine and it is prepared commercially by chitin deacetylation
The present work focused on the evaluation of chitosan and their different UV/ ozone derivatives properties such as antimicrobial, antioxidant, fibrinolytic and anticoagulation activities
This study focused in evaluating the effect of extracted chitosan and their UV/Ozone derivatives in different bioactivities as antimicrobial, antioxidant, anticoagulation and fibrinolytic activities
Summary
Chitosan is a cationic linear polysaccharide containing randomly dispersed β-(1-4)-linked D-glucosamine and N-acetylD-glucosamine and it is prepared commercially by chitin deacetylation. Evaluation of the degree of deacetylation (DDA) is important for the determination of their chemical content, possessions and structure-properties relationship. UV/ozone modification is useful as it is applicable to an extensive range of organic substrates with little or no pretreatment. Both the physicochemical and topographical effects of UV/ozone treatment may affect the spatial organization of cells. Multifunction property of chitosan encourages the researchers to put it in different forms by chemical modifications or UV exposure aiming to improve their biological activities from the point that wavelength ultraviolet radiation could causechemical reactionsand causes change in chemical structure (Ferrero, 2015). Increasing of irradiation time led to more chitosan degradation (Sionkowska et al, 2014)
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