Abstract
A study was undertaken to evaluate the genetic link of Tharu community with South and East Asian populations. Tharu is an intriguing community that lives in the Terai region of Himalayas. The folklore claims that they originally came from Rajasthan. Previous studies have analyzed uniparental and biparental markers to access their origin and affinity. This is first genetic study based on 20 autosomal STR genetic markers included in the PowerPlex® 21 multiplex system in the Tharu population of India. The wide range of heterozygosity (0.61963 to 0.92025) indicates multidirectional gene flow in the studied population. The locus Penta E was most polymorphic and discriminatory with a value of 0.907 and 0.979 respectively, whereas the locus TPOX was least polymorphic and discriminatory with a value of 0.578 and 0.798 respectively among all the studied loci. The combined value of matching probability and paternity index was observed as 4.2 × 10−24 and 6.01 × 108 respectively. The results showed no deviation from Hardy–Weinberg equilibrium. All the studied loci showed significant genetic variation when compared with previously reported populations. This study suggests that the studied population has an admixed origin with more inclination towards the populations having a higher genetic relationship with East Asian rather than South Asian populations.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
