Abstract

Results: Mean CCT and CTmin values were significantly lower in the patient group than in the control group (P < 0.01). Mean CP and DCP values were higher in the patients than in the control group (P < 0.001). Although mean I-S values were not statistically different, 11 eyes in the Down syndrome group and 3 eyes in the control group had 1.20 or higher I-S. Eleven eyes (21.1%) in the patient group and 1 eye (1.7%) in the control group had subclinical keratoconus (P < 0.01), and 20 eyes (38.4%) in the case group and 2 eyes (3.3%) in the control group had at least 1 abnormal parameter (P < 0.01). Conclusion: Corneal abnormalities and subclinical keratoconus are more common in children with Down syndrome.

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