Evaluation of doses distribution in breast cancer mastectomy using SlicerRT

Abstract

Treatment planning aimed to provide the maximum dose to target tumor and minimize doses received by healthy tissue. Dose-volume histograms contain essential information about the dose distribution that radiation oncologists use in considering a treatment planning. In breast cancer mastectomy, the thickness of the thorax wall has decreased because of surgery. Therefore it is necessary to analyze the dose received by healthy tissue around the tumor. This study analyzes the doses distribution in breast cancer mastectomy using SlicerRT and compares it with treatment planning from the hospital. The study used three data patients from MRCCC Siloam Hospitals Jakarta. The simulation results were analyzed based on the International Commission on Radiation Units and Measurements Report’s 83 for target tumor and tolerance limits of healthy tissue according to limitations from various references. Although the target tumor’s homogeneity does not qualify, the healthy tissue around the tumor is still within tolerance. It is not a problem in intensity-modulated radiation therapy if avoidance of healthy tissue is more important than homogeneity. For the comparison result, the percentage acceptance of SlicerRT simulation is quite good, above 90%.