Abstract
The purpose of this study was to assess the accuracy and efficacy of an automated treatment plan verification, or “secondary check”, tool (Mobius3D), which uses a reference dataset to perform an independent three‐dimensional dose verification of the treatment planning system (TPS) dose calculation and assesses plan quality by comparing dose‐volume histograms to reference benchmarks. The accuracy of the Mobius3D (M3D) system was evaluated by comparing dose calculations from IMRT and VMAT plans with measurements in phantom geometries and with TPS calculated dose distributions in prostate, lung, and head and neck patients (ten each). For the patient cases, instances of DVH limits exceeding reference values were also recorded. M3D showed agreement with measured point and planar doses that was comparable to the TPS in phantom geometries. No statistically significant differences (p<0.05) were noted. M3D dose distributions from VMAT plans in patient cases were in good agreement with the TPS, with an average of 99.5% of dose points showing γ5%,3mm<1. The M3D system also identified several plans that had exceeded dose‐volume limits specified by RTOG protocols for those sites. The M3D system showed dosimetric accuracy comparable with the TPS, and identified several plans that exceeded dosimetric benchmarks. The M3D system possesses the potential to enhance the current treatment plan verification paradigm and improve safety in the clinical treatment planning and review process.PACS number: 87.55.D‐, 87.55.km, 87.55.Qr,
Highlights
208 Fontenot et al.: Radiotherapy treatment plan verification phantom to ensure data transfer fidelity and deliverability of the treatment plan
Because the algorithm is implemented on a graphical processing unit (GPU), calculations are purported to require less time compared to the existing treatment planning system (TPS) that utilize a similar dose calculation algorithm.[7]
The treatment field information is passed to the dose calculation algorithm, which uses this information to calculate the three-dimensional dose distribution within the CT dataset associated with the plan
Summary
208 Fontenot et al.: Radiotherapy treatment plan verification phantom to ensure data transfer fidelity and deliverability of the treatment plan. Despite increased complexity of treatment planning dose distributions, the methods and algorithms employed by “secondary check” systems have remained largely unchanged: dose calculations to a single point using simple heterogeneity corrections. Such limitations inevitably lower the ability of those systems to detect clinically meaningful errors in the TPS calculation throughout the high-dose volume. An additional limitation of the current “secondary check” paradigm of calculating dose to a single point, aside from precluding a full three-dimensional verification of the TPS accuracy, precludes an independent assessment of the quality of the treatment plans with respect to dosimetric benchmarks. There is a potential role for more sophisticated treatment planning dose verification tools to enhance current clinical practice
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
