Abstract
Background/Purpose: Celiac plexus neurolysis (CPN) is used for pain management in pancreatic cancer. It involves the injection of alcohol to destroy the celiac neural structures, aimed at achieving longer-lasting analgesia than a steroid/anesthetic block alone (CPB). However, one concern in chronic pancreatitis is that subsequent surgery may prove difficult due to adhesions. The aim of the study was to determine the degree of interference and the adhesion burden from CPN vs. CPB in a blinded pig survival model.
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