Abstract
Key Clinical MessageEtomidate is a very effective drug in severe Cushing's syndrome that is refractory to ketoconazol. Control of the serum cortisol levels in ectopic Cushing's syndrome can be obtained with infusion rates much lower than those used in anesthesia, without respiratory side effects.
Highlights
Control of the serum cortisol levels in ectopic Cushing’s syndrome can be obtained with infusion rates much lower than those used in anesthesia, without respiratory side effects
We report the case of a 51-year-old female with Cushing’ syndrome due to ectopic ACTH secretion caused by a pancreatic tumor with a liver metastatic lesion (Fig. 1)
In April 2017, she had the following tests: 24-h urinary-free cortisol: 3509.45 lg/24 h (58–403), morning serum cortisol: 58.73 lg/dL (6.7–22.6), ACTH: 1060 pg/mL (10–100), TSH: 0.41 mIU/L (0.3–5), free T4: 0.91 ng/dL (0.63– 1.34), FSH: 0.50 mIU/mL (16.74–113.59), LH: 0.36 mIU/ mL (10.87–58.64), estradiol: 20.0 pg/mL (
Summary
Etomidate is a very effective drug in severe Cushing’s syndrome that is refractory to ketoconazol. Control of the serum cortisol levels in ectopic Cushing’s syndrome can be obtained with infusion rates much lower than those used in anesthesia, without respiratory side effects. Ectopic Cushing’s syndrome, etomidate, metastatic carcinoma, octreoscan.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
