Abstract
Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease with higher incidence and increased disease severity, including increased medication requirements and morbidity, in people not uniquely of European descent. Few studies explore the differences between ethnic groups at presentation and early in the disease process, and no studies exist to our knowledge specifically evaluating the pediatric Hispanic population. We hypothesize, based on clinical experience, that pediatric SLE patients of Hispanic descent have an earlier, more severe disease course compared to patients of European descent.
Highlights
Systemic lupus erythematosus (SLE) is an autoimmune disease with higher incidence and increased disease severity, including increased medication requirements and morbidity, in people not uniquely of European descent
We retrospectively reviewed the charts of 43 patients with diagnosis of SLE prior to age 18 currently followed at the pediatric rheumatology clinic of an urban tertiary-care center
HA pSLE patients presented with more ACR criteria within 6 months of diagnosis compared to EA (4.5 vs. 3.5; p = 0.04)
Summary
Ethnic differences in pediatric SLE early disease severity: a comparison between HispanicAmericans and European-Americans. Peony Liu2*, Jennifer MP Woo, Miriam F Parsa, Gil Amarilyo, Deborah K McCurdy, Ornella J Rullo. From 2011 Pediatric Rheumatology Symposium sponsored by the American College of Rheumatology Miami, FL, USA. Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease with higher incidence and increased disease severity, including increased medication requirements and morbidity, in people not uniquely of European descent. Few studies explore the differences between ethnic groups at presentation and early in the disease process, and no studies exist to our knowledge evaluating the pediatric Hispanic population. We hypothesize, based on clinical experience, that pediatric SLE patients of Hispanic descent have an earlier, more severe disease course compared to patients of European descent
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
