Abstract
Hypertensive diseases are still a leading cause of death among mothers all over the world. It’s complicated aetiology, which begins with aberrant placentation and ends with endothelial dysfunction, is yet unknown. The goal of this study is to learn about changes in serum and urine calcium levels in women who have Gestational Hypertension. 200 normotensive pregnant women between 24-28 weeks were included in the study based on inclusion and exclusion criteria. Urine calcium and creatinine and serum uric acid, total protein, albumin and serum sodium were estimated in corresponding samples collected from patients. The study showed a sensitivity of 80%, specificity of 71%, positive predictive value was 77%, negative predictive value 74%, and diagnostic accuracy as 74%. A single estimation of calcium to creatinine ratio in asymptomatic pregnant women between 24-28 week of gestation is a simple and cost-effective test.
Highlights
Physiological and anatomical alterations occurring in the body
More emphasis is laid in the Pregnancy is a physiological stress associated biochemical changes seen in the blood during the with many complex and interrelated biochemical, Giresh; JPRI, 33(45B): 353-357, 2021; Article no.JPRI.72127 normal pregnancy and are exaggerated in various complications of pregnancy [1]
The symptoms are thought to be a late symptom of an illness that has been present from the first trimester of pregnancy
Summary
Physiological and anatomical alterations occurring in the body. More emphasis is laid in the Pregnancy is a physiological stress associated biochemical changes seen in the blood during the with many complex and interrelated biochemical, Giresh; JPRI, 33(45B): 353-357, 2021; Article no.JPRI.72127 normal pregnancy and are exaggerated in various complications of pregnancy [1]. The symptoms are thought to be a late symptom of an illness that has been present from the first trimester of pregnancy Because of this "diagnostic delay," various tests have been developed to diagnose preeclampsia as soon as feasible, frequently even before the patient manifests arterial hypertension [2,3]. There is a constant need to conduct studies to explore a screening tool for the prediction of preeclampsia which is easy to carry out, non-invasive and not much expensive in Indian setup [4,5] To this purpose, the present study was carried out" To investigate the significance of urinary calcium for prediction of pregnancy induced hypertension and may identify population at greater risk to be included in primary prevention programme
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