Abstract

Drug analysis plays an important role in the development, manufacture and therapeutic use of drugs. The standard analytical procedure for newer drugs or formulation may not be available in pharmacopoeia. Hence, it is essential to develop newer analytical methods which are accurate, precise, specific, linear, simple and rapid. So, an attempt was made to develop simple, cost effective accurate spectroscopic methods for nitazoxanide. A simple, sensitive spectrophotometric method in UV region was developed for the determination of nitazoxanide in bulk and tablet dosage forms. Nitazoxanide is a new anti-protozoal drug, which showed maximum absorbance at 346nm with apparent molar absorptivity of 23783.92 Lmol-1cm-1. Beers law obeyed in the concentration range of 2-14?g/ml. According to ICH guidelines, results of the analysis were validated statistically and by recovery studies.

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