Abstract

We examined the time course of prossure development after temporary occlusion of the airway to develop guidelines for estimating inspiratory muscle strength in mechanically ventilated patients. Twenty critically ill patients were tested by two methods, one involving total airway occlusion at end-exhalation (Method I) and the other involving use of a unidirectional expiratory valve to selectively permit exhalation while inspiration was blocked (Method II). With either technique, maximally negative pressures (MIP) were not achieved until approximately ten efforts or 20 seconds had elapsed postocclusion. Maximal pressures achieved by Method II almost invariably exceeded those achieved by Method I (mean Δ = 34%, P

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