Abstract
Contraceptives are intentional prevention of conception through the use of various devices sexual practices, chemicals, drugs or surgical procedures become a contraceptive if its purpose is to prevent a woman from becoming pregnant. This is a cross sectional study conducted at ALnow Hospital Khartoum, Sudan, the study aimed to estimate D.dimer levels among Sudanese women take contraceptive pill. 50 Women uses contraceptive pill used as a cases and 50 apparently health women were used as a control. Three ml of venous blood samples were collected from each subject in 3.8% tri-sodium citrate (9:1 vol/vol) for D-dimer analysis. The study revealed that was clearly significant increase in D.dimer in women take oral contraceptive pill (p.value 0.000), also the study concluded that D-dimer level was increased in users oral contraceptive Sudanese women, that is increase the coagubility of the blood and might be become as a risk factor. 
 Keywords: Contraceptive pills, D.dimer, coagubility.
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