Abstract

Essential thrombocytosis (ET) is a rare myeloproliferative disorder, which is a major risk factor for thrombosis and bleeding, which complicates cardiovascular surgery. ET is a risk factor for coronary artery disease that should be treated. We present a case of a male with ET who underwent coronary artery bypass grafting (CABG) at the University Hospital of the West Indies, and died post-surgery. Post mortem revealed early graft thrombosis. We believe that post-operative aspirin therapy maybe would have prevented this fatal outcome.

Highlights

  • We present a case of a male with Essential thrombocytosis (ET) who underwent coronary artery bypass grafting (CABG) at the University Hospital of the West Indies, and died post-surgery

  • Coronary artery disease (CAD) exhibiting symptoms usually suggest an etiology of obstructive disease due to underlying atherosclerosis

  • ET is a myeloproliferative disorder with a sustained elevated platelet count of greater than 800 × 109/L, which can result in serious complications of arterial and venous thrombosis as well as bleeding in patients undergoing cardiovascular surgery

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Summary

Introduction

Coronary artery disease (CAD) exhibiting symptoms usually suggest an etiology of obstructive disease due to underlying atherosclerosis. CAD may be due to unusual causes and should prompt further investigations. Patients with ET can present with cerebrovascular disease and ischemic stroke as well. This demonstrates ET as a predisposing factor for vasculopathies. ET is a myeloproliferative disorder with a sustained elevated platelet count of greater than 800 × 109/L, which can result in serious complications of arterial and venous thrombosis as well as bleeding in patients undergoing cardiovascular surgery. These complications can arise during or immediately after cardiovascu-. We report the case of a patient with ET who underwent CABG and subsequent died as a result of early postoperative graft thrombosis and occlusion

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