Abstract
The antimicrobial activity of essential oils (EOs) has been known for ages; in particular, the EOs of Melaleuca alternifolia, Thymus vulgaris, Mentha piperita, and Rosmarinus officinalis have been used for the treatment of fungal and bacterial infections. This study focused on the in vitro cytotoxicity to normal human conjunctiva cells and antimicrobial activity of 20 EOs. The oils tested showed no cytotoxic effect at very low concentrations. Rosmarinus officinalis, Melaleuca alternifolia, and Thymus vulgaris L. red thyme geraniol sel oils had good antimicrobial activity against Gram-positive and Gram-negative strains. The results of this study are of great interest and may have a major impact on public health, providing useful tips to optimize the therapeutic use of some natural drugs.
Highlights
The antimicrobial activity of essential oils (EOs) has been known for ages; in particular, the EOs of Melaleuca alternifolia, Thymus vulgaris, Mentha piperita, and Rosmarinus officinalis have been used for the treatment of fungal and bacterial infections
The antimicrobial activity of EOs has been well known for many years; in particular, the essential oils of Melaleuca alternifolia, Thymus vulgaris, Mentha piperita, and Rosmarinus officinalis have been used for the treatment of fungal and bacterial infections
This study focused on the in vitro cytotoxicity to normal human conjunctiva cells and antimicrobial activity of 20 EOs
Summary
The antimicrobial activity of essential oils (EOs) has been known for ages; in particular, the EOs of Melaleuca alternifolia, Thymus vulgaris, Mentha piperita, and Rosmarinus officinalis have been used for the treatment of fungal and bacterial infections. Essential oils (EOs) have been used since ancient times for various purposes, including cosmetics and cuisine [1]. They were and still are used in the medical field because of their therapeutic properties. Their use was part of the ritual tradition of almost all cultures [2]; in the East, aromatic substances were often regarded as much more than just perfumes and were employed for both liturgical and therapeutic purposes, and the Ebers Papyrus records the use of many medicinal herbs, oils, and perfumes. Thanks to the scientific revolution at the beginning of the nineteenth century, chemists were able to identify the various components of the EOs and develop the modern pharmaceutical industry
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