Abstract
Eruptive xanthomas are characterized by large numbers of yellow papules, typically 1-4 m in size, sometimes with an erythematous halo, sometimes pruritic, of sudden onset and generally observed on the extensor surfaces of the extremities. These are seen in less than 0.1% of diabetic patients. Diabetes mellitus is the most common secondary cause of type 5 hyperlipoproteinemia, a form of chylomcronemia. Eruptive xanthomas generally emerge at triglyceride levels above 2000 mg/dL proceeding with chylomicronemia. This case report of a 36-year-old woman diagnosed with eruptive xanthoma on the basis of clinical and histopathological findings is presented in order to emphasize that these are an important finding of diseases associated with metabolic syndrome, such as diabetes mellitus and hypertriglyceridemia.
Highlights
Eruptive xanthomas generally appear at a triglyceride level above 2000 mg/dL proceeding with chylomicronemia
We describe a case of eruptive xanthomas in a 36-year-old female patient in order to emphasize an important finding of diseases associated with metabolic syndrome, such as diabetes mellitus and hypertriglyceremia, capable of causing severe complications such as atherosclerosis and acute pancreatitis
Eruptive xanthoma was diagnosed on the basis of significant high hypertriglyceridemia and hyperglycemia
Summary
Eruptive xanthomas are seen in fewer than 0.1% of diabetic patients. Diabetes mellitus is the most common secondary cause of type 5 hyperlipoproteinemia, a form of chylomicronemia. Eruptive xanthomas generally appear at a triglyceride level above 2000 mg/dL proceeding with chylomicronemia. They are generally characterized by yellow papules of sudden onset, typically 1-4 mm in diameter, sometimes surrounded by an erythematous halo, that are usually observed in large numbers on the extensor surfaces of the extremities.
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