Abstract
Transurethral Resection of Prostate (TURP) has been the gold standard of surgical management in Benign Prostatic Hyperplasia (BPH) patients. Various techniques, including laser therapy, have been developed to provide a safe alternative to TURP. The effect of the laser on the patient's erectile function, however, is still unknown. The aim of this study is to evaluate the erectile function of individuals with BPH undergoing surgical intervention with laser procedure compared to the standard TURP procedure. A systematic search was conducted through PubMed and Science-Direct databases up to September 2021. All studies comparing laser therapy to TURP for patients with BPH and reporting the final International Index of Erectile Function (IIEF) and change of IIEF were included in this study. A total of three Randomized Controlled Trials (RCTs) and one retrospective study were included in the final analysis. According to the meta-analysis, laser therapy had a similar final IIEF score during the 12-month follow-up compared to the TURP procedure in the subgroup of IIEF-15, IIEF-5, and the combined analysis (p=0.62, p=0.72, p=0.79, respectively). The change of IIEF from baseline was similar among both modalities (p = 0.8). The effect of laser therapy on erection function was similar to the TURP procedure.
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