Abstract

Objective: Using data from cancer registries to estimate thyroid cancer incidence and mortality in China, 2015.Methods: Data submitted from local cancer registries were checked and evaluated according to the criteria of data quality control, a total of 368 cancer registries' data were qualified for the final analysis. Data were stratified by area (urban/rural, eastern/central/western), sex and age, combined with national population data to estimate thyroid cancer incidence and mortality in China, 2015.Results: Approximately 200,700 new cases were diagnosed in 2015, accounting for 5.11% of all cancer cases. The crude incidence rate was 14.60/100,000. Age-standardized incidence rates by Chinese standard population (ASIRC) and world standard population (ASIRW) were 12.05/100,000 and 10.44/100,000, with the cumulative incidence rate (0–74 years old) of 1.00%. About 7,900 deaths of thyroid cancer were reported in 2015, accounting for 0.34% of all cancer deaths. The crude mortality rate was 0.58/100,000, age-standardized mortality rates by Chinese standard population (ASMRC) and world standard population (ASMRW) were 0.37/100,000 and 0.36/100,000. The age-standardized incidence and mortality in females were significantly higher than those in males (P < 0.001). The rates in urban areas were higher than those in rural areas (P < 0.001). The ASIRC in eastern areas was higher than that in central and western areas (P < 0.001), while the ASMRC in central areas was higher than that in eastern and western areas (P < 0.001).Conclusions: The burden of thyroid cancer was heavy in China, cancer control faces the problem of the disparity between geographic areas, and the incidence and mortality rates were varied by sex and age. Targeted cancer preventive measures should be put into practice.

Highlights

  • Thyroid cancer is the most common endocrine and head-andneck malignancy globally

  • In 2015, the estimated new cases diagnosed with thyroid cancer were 200,700 in China, accounting for 5.11% of all new cancer cases, with the incidence rate ranked 7th in all kinds of cancer

  • Thyroid cancer was found burdened with the high incidence, the mortality rate remained relatively low in China in 2015

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Summary

Introduction

Thyroid cancer is the most common endocrine and head-andneck malignancy globally. Paes et al reported in a research in 2010 that thyroid cancer incidence is rising at a rate that is the fastest of all malignancies [1]. According to the Global Cancer Observatory (GLOBOCAN) 2018 from International Agency for Research on Cancer (IARC), about 567,200 new cases were diagnosed, and 41,100 deaths were caused by thyroid cancer in 2018 [2]. The incidence rate of thyroid cancer is increasing in China. According to the annual report of China Cancer Registry 2018, thyroid cancer has become one of the 10 major cancers threatening the health of Chinese residents [3]. Some researchers have reported the incidence and mortality rates of thyroid cancer in the regional level [5,6,7], while the nationwide data is still lacked. As national cancer registration data were not publicly available in the same fashion as the Surveillance, Epidemiology, and End Results

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