Abstract

Currently, bacterial resistance situation in health care settings is very serious in China, and the prevalence of a variety of common multidrug-resistant bacteria and pan-resistant bacteria are relatively high. Drug-resistant bacteria in Gram-positive bacteria are mainly methicillin resistant Staphylococcus aureus (MRSA) and macrolide-resistant Streptococcus, while glycopeptide-resistant enterococci are still at a low level. The clonal distribution of MRSA and mechanisms of Streptococcus resistance in China are different from those in European and American countries. Cephalosporins and quinolones resistance are the marked characteristic of Enterobacteriaceae with a high occurrence over 60%. Carbapenem-resistant Klebsiella pneumoniae shows a rapid upward trend, and producing KPC-2 type carbapenemases is the main mechanism of its resistance. Resistance in Pseudomonas aeruginosa is relatively stable, with resistant rates ranging from 20% to 30%. Multi-drug resistant Acinetobacter baumannii is a big problem in clinic. More than 50% Acinetobacter baumannii strains are resistant to carbapenems and cephalosporins, and tigecycline-resistant Acinetobacter baumannii is increasing. This paper systematically reviews the status and characteristics of bacterial resistance in last five years with referring to the surveillance data of antimicrobial resistance and the findings of related mechanisms. Key words: Methicillin-resistant Staphylococcus aureus; Streptococcus pneumonia; Enterococcus; Carbapenem-resistant Enterobacteriaceae; Pseudomonas aeruginosa; Acinetobacter; Epidemiology; Molecular characteristics

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.