Abstract
From November 2016 to April 2017, a cross-sectional study to determine the sero-prevalence of contagious caprine pleuropneumonia (CCPP) and to investigate its epidemiology was conducted in selected districts of Borana zone in Ethiopia. In addition, the study aimed at identifying Mccp antigens using species specific primer of PCR. A multistage random sampling was implemented to select districts, pastoral associations (villages), and households. A total of 890 serum samples of small ruminants that had not been vaccinated (goats n = 789 and sheep n = 101) were collected and screened for the presence of antibodies against Mycoplasma capricolum subspecies capripneumoniae using a competitive enzyme-linked immunosorbent assay. Lung tissues and pleural fluid samples were collected from 3 sero-positive and clinically suspected goats for isolation of Mycoplasma capricolum subspecies capripneumoniae. Serology showed that overall 31.2% (246/789) of goats and 12.9% (13/101) of sheep were positive with statistically significant differences between districts (p = 0.001). Multivariable logistic regression analysis revealed that goats from Moyale and Yabello districts had higher odds of being positive than goats from Elwoya district with odd ratios of 2.05 and 1.61, respectively. Age of goats was also significantly associated with sero-positivity (OR = 1.47; CI 95% 1.2–1.8). Mycoplasma capricolum subspecies capripneumoniae was identified in 6 (75%) of the tissue samples using species-specific primer of PCR. Besides improving the understanding of the epidemiology of CCPP in the selected districts and demonstrating its wide distribution, the study highly also provides evidence of the possible role of sheep in the maintenance of the disease.
Highlights
Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subspecies capripneumoniae (Mccp) is a severe and devastating respiratory disease with high morbidity and mortality in goats (Sadique et al 2012; Tsehay et al 2014), causing considerable economic losses (Asmare et al 2016)
Survey result on symptoms of CCPP observed
There was a significant difference in the sero-prevalence CCPP between different age groups (p < 0.001) in which adult goats (37.3%) were more likely to test positive than young goats (24.7%)
Summary
Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subspecies capripneumoniae (Mccp) is a severe and devastating respiratory disease with high morbidity and mortality in goats (Sadique et al 2012; Tsehay et al 2014), causing considerable economic losses (Asmare et al 2016). It occurs in many countries in Africa, Asia, and Middle East (Prats-van der Ham et al 2015) and is a classical trans-boundary animal disease (Shahzad et al 2016). Abortion and high mortality rates have been reported (Wazir et al 2016)
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