EP967 Natural history of patients with BRCA-mutated high grade epithelial ovarian cancer (HGEOC) before the era of PARP inhibitors maintenance in 1st line treatment

Clémence Romeo ,Patricia Pautier ,Emmanuel Barranger ,Laurence Gladieff ,Anne Floquet ,Thierry Petit ,Sophie Gourgou ,Roman Rouzier ,Loı̈c Campion ,Classe Jm ,Éric Leblanc ,François Marchal ,A.m Savoye ,Pierre Méeus ,Manuel Rodrigues ,Coralie Courtinard ,Christophe Pomel ,Isabelle Ray‐Coquard ,Cécile Guillemet ,S Causeret ,Magali Provansal ,Claire Labreveux ,T De La Motte Rouge ,Florence Joly

doi:10.1136/ijgc-2019-esgo.1013

EP967 Natural history of patients with BRCA-mutated high grade epithelial ovarian cancer (HGEOC) before the era of PARP inhibitors maintenance in 1st line treatment

Clémence Romeo , Patricia Pautier + Show 22 more

https://doi.org/10.1136/ijgc-2019-esgo.1013

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Journal: International Journal of Gynecologic Cancer	Publication Date: Nov 1, 2019
Citations: 2

Affiliation: Centre Léon Bérard, Institut Gustave Roussy, Centre Antoine Lacassagne, Institut Claudius Regaud, Institut Bergonié, Institute of Cancer Research of Montpellier, Institute Curie, Institut de Cancérologie de l'Ouest, Centre Oscar Lambret, Institut de Cancérologie de Lorraine, Institut Jean Godinot, UniCancer Group, Centre Jean Perrin, Centre Georges François Leclerc, Institute Paoli-Calmettes, Centre Eugène Marquis, Centre François Baclesse

#High Grade Epithelial Ovarian Cancer #BRCA2 Mutation + Show 8 more

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Abstract

Introduction/BackgroundIn SOLO1 trial, maintenance therapy with olaparib considerably improved progression-free survival (PFS) among women with newly-diagnosed, advanced BRCA-mutated HGEOC. Based on the large real-life ESME ovarian cancer (OC) cohort, we...

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