Abstract

The chemotherapy including the multitargeted antifolate (pemetrexed disodium; Alimta) is indicated for the 1st line treatment of patients with advanced non-small cell lung cancer (NSCLC). It is constructed by induction and maintenance chemotherapy, and some patients have the response over 12 months. We evaluated SLIT2 expression of immunohistochemistry (IHC) in NSCLC with long-term response to pemetrexed.

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