Abstract
Objectives There is a debate on the potential advantageous effects of bilateral subthalamic deep brain stimulation (DBS) in the treatment of Parkinson’s disease (PD) with early fluctuations. Our investigation aimed to evaluate if DBS therapy could preserve working capability. Materials & methods We reviewed the data of 40 young ( Results Although similar (approximately 50%) improvement was achieved in the severity of motor and major non-motor symptoms in both groups, the postoperative quality of life was significantly better in the ‘Active job’ group (0.687 vs. 0.587, medians, p Conclusions Although our study has several limitations, our results suggest that in patients with active job the appropriately ‘early’ usage of DBS might help preserve working capability in a two-year time-frame and gain higher improvement in quality of life.
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