Abstract

Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare vasculitis, initially presenting with asthma, chronic rhinosinusitis with nasal polyps (CRSwNP) and striking peripheral eosinophilia. Ultimately, in the vasculitic stage, peripheral neuropathy, purpura, or other organ involvement occurs. Diagnosis is often delayed as only 40% of patients are p-anti-neutrophil cytoplasmic antibodies (ANCA) positive. We present three patients presenting with AERD, who were ultimately diagnosed with EGPA.

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