Environmental and Economic Impacts of End-tidal Control of Volatile Anesthetics: A Scoping Review and Analysis

e13644 Background: Climate change due to greenhouse gas (GHG) emissions by humans imperils health. Health care is a major source of GHG emissions and thus reducing health care’s environmental impact should be a global priority. GHG emissions associated with the production and administration of cancer drugs, as well the downstream societal costs in human health terms, are undescribed. The extent to which a given cancer drug’s dosing frequency and duration impact GHG emissions is unknown. Methods: Using trastuzumab for HER2-positive breast cancer as a use case, we conducted a case-control simulation study of single, U.S. academic medical center data to estimate the expected reductions in GHG emissions with three alternative dosing strategies (6-month adjuvant treatment duration, extended-interval dosing, and both) using streamlined life-cycle analysis. We estimated the per-patient relative reduction in GHG emissions expected to occur with each of the alternative dosing strategies and, in exploratory analysis, the societal health costs ( e.g., disability-adjusted life-years [DALYs] and excess mortality per kg CO2) associated with therapy-related GHG emissions, using conventional versus alternative dosing strategies. Results: Adoption of 6-month adjuvant trastuzumab reduced expected per-patient GHG emissions in the adjuvant setting by 10%. Adoption of both 6-month adjuvant trastuzumab and pharmacokinetically-supported every 4-week trastuzumab dosing reduced GHG emissions by 4.5%, 18.7%, and 14.6% in the neoadjuvant, adjuvant, and metastatic settings, respectively. An estimated 8.1 DALYs and 4.6 excess lives are lost annually worldwide as a result of U.S.-based administration of conventionally dosed trastuzumab. Adoption of alternative dosing in the U.S. is estimated to enable avoidance of approximately 1.5 DALYs and 0.9 excess lives lost annually. Conclusions: Alternative dosing strategies, suggested to be noninferior by pharmacokinetic and clinical evidence, are estimated to reduce the societal health costs imposed on bystanders that arise from cancer care’s environmental impact. Environmental impact and its resultant societal health costs should be considered in clinical trial design, re-interpretation of previously conducted trials, regulatory decision-making, and health technology assessments of both new and existing cancer therapies.

Major US electric utility climate pledges have the potential to collectively reduce power sector emissions by one-third

The potential of the EAT-Lancet reference diet, which promotes a healthy diet within planetary limits, to reduce greenhouse gas emissions (GHGe) remains understudied. This study examines the role of nutritional and acceptability constraints in reducing GHGe through diet optimization, and tests the alignment between GHGe reduction and the EAT-Lancet score.The study used data from 29,413 NutriNet-Santé participants to model French diets and evaluate their environmental, nutritional, economic, and health impact. The Organic Food Frequency Questionnaire was used to assess organic and conventional food consumed, and the Dialecte database was used to estimate the diet environmental impacts. Quality of diets were also evaluated based using the PNNS-GS2 (Programme National Nutrition-Santé 2 guidelines score).When testing minimizing GHGe under strict nutritional and acceptability constraints, it was possible to reduce GHGe up to 67 % (from 4.34 in the observed diet to GHGe = 1.45 kgeqCO2/d) while improving the EAT score by 103 % with 91 % of the food as organic. Greater reductions required relaxation of some constraints.When testing maximizing EAT score under gradual reduction in GHGe, the adherence to the EAT-Lancet diet was not significantly affected by the gradual reduction in GHGe. To maximize EAT score with 75 % reduction in GHGe (1.09 kgeqCO2/d), less strict constraints on the bioavailability of iron and zinc are necessary. The EAT score improved by 141 %, while land occupation decreased by 57 %, compared to the observed value. The diet contained 94 % of organic foods.There was some alignment between the degree of adherence to the EAT-Lancet diet and the reduction in GHGe, but other diets may also lead to a strong reduction in GHGe. Thus, GHGe can be greatly reduced by dietary choices, but require profound reshaping of diets which must be coupled with changes in other areas of the food chain.

Modelling the effect on chronic disease health of changing food prices based on greenhouse gas emissions

Life cycle assessment for co-firing semi-carbonized fuel manufactured using woody biomass with coal: A case study in the central area of Wakayama, Japan

Greenhouse gas (GHG) emissions reduction in the electricity sector: Implications of increasing renewable energy penetration in Ghana's electricity generation mix

Transitioning to Environmentally Sustainable, Climate-Smart Radiation Oncology Care

Harmonizing the quantification of CCS GHG emission reductions through oil and natural gas industry project guidelines

In this study, we selected the production processes and main products of three typical chemical enterprises in Shanghai, namely SH Petrochemical (part of the oil-refining sector), SK Ethylene, and HS Chlor-Alkali, to quantitatively assess the synergistic effects across technology, policy, and emission mechanisms. The localized air pollutant levels and greenhouse gas emissions of the three enterprises were calculated. The synergistic effects between the end-of-pipe emission reductions for air pollutants and greenhouse gas emissions were analyzed using the pollutant reduction synergistic and cross-elasticity coefficients, including technology comparisons (e.g., acrylonitrile gas incineration (AOGI) technology vs. traditional flare). Based on these data, we used the SimaPro software and the CML-IA model to conduct a life cycle environmental impact assessment regarding the production and upstream processes of their unit products. By combining the life cycle method and the scenario simulation method, we predicted the trends in the environmental impacts of the three chemical enterprises after the implementation of low-carbon development policies in the chemical industry in 2030. We also quantified the synergistic effects of localized air pollutant and greenhouse gas (GHG) emission reductions within the low-carbon development scenario by using cross-elasticity coefficients based on life cycle environmental impacts. The research results show that, for every ton of air pollutant reduced through end-of-pipe treatment measures, the HS Chlor-Alkali enterprise would increase its maximum CO2 emissions, amounting to about 80 tons. For SK Ethylene, the synergistic coefficient for VOC reduction and CO2 emissions when using AOGI thermal incineration technology is superior to that for traditional flare thermal incineration. The activities of the three enterprises had an impact on several environmental indicators, particularly the fossil fuel resource depletion potential, accounting for 69.48%, 53.94%, and 34.23% of their total environmental impact loads, respectively. The scenario simulations indicate that, in a low-carbon development scenario, the overall environmental impact loads of SH Petrochemical (refining sector), SK Ethylene, and HS Chlor-Alkali would decrease by 3~5%. This result suggests that optimizing the upstream power structure, using “green hydrogen” instead of “grey hydrogen” in hydrogenation units within refining enterprises, and reducing the consumption of electricity and steam in the production processes of ethylene and chlor-alkali are effective measures in reducing carbon emissions in the chemical industry. The quantification of the synergies based on life cycle environmental impacts revealed that there are relatively strong synergies for air pollutant and GHG emission reductions in the oil-refining industry, while the chlor-alkali industry has the weakest synergies.

Energy-related activities are a major contributor of greenhouse gas (GHG) emissions. A growing body of knowledge clearly depicts the links between human activities and climate change. Over the last century the burning of fossil fuels such as coal and oil and other human activities has released carbon dioxide (CO2) emissions and other heat-trapping GHG emissions into the atmosphere and thus increased the concentration of atmospheric CO2 emissions. The main human activities that emit CO2 emissions are (1) the combustion of fossil fuels to generate electricity, accounting for about 37% of total U.S. CO2 emissions and 31% of total U.S. GHG emissions in 2013, (2) the combustion of fossil fuels such as gasoline and diesel to transport people and goods, accounting for about 31% of total U.S. CO2 emissions and 26% of total U.S. GHG emissions in 2013, and (3) industrial processes such as the production and consumption of minerals and chemicals, accounting for about 15% of total U.S. CO2 emissions and 12% of total ...

Alternative methodologies for the reduction of greenhouse gas (GHG) emissions from crude palm oil (CPO) production by a wet extraction mill in Thailand were developed. The production of 1 t of CPO from mills with biogas capture (four mills) and without biogas capture (two mills) in 2010 produced GHG emissions of 935 kg carbon dioxide equivalent (CO2eq), on average. Wastewater treatment plants with and without biogas capture produced GHG emissions of 64 and 47% of total GHG emission, respectively. The rest of the emissions mostly originated from the acquisition of fresh fruit bunches. The establishment of a biogas recovery system must be the first step in the reduction of GHG emissions. It could reduce GHG emissions by 373 kgCO2eq/t of CPO. The main source of GHG emission of 163 kgCO2eq/t of CPO from the mills with biogas capture was the open pond used for cooling of wastewater before it enters the biogas recovery system. The reduction of GHG emissions could be accomplished by (i) using a wastewater-dispersed unit for cooling, (ii) using a covered pond, (iii) enhancing the performance of the biogas recovery system, and (iv) changing the stabilization pond to an aerated lagoon. By using options i-iv, reductions of GHG emissions of 216, 208, 92.2, and 87.6 kgCO2eq/t of CPO, respectively, can be achieved.

For all its cachet, you might think that hybrid drivetrain technology is inherently green. But only 13 of 34 hybrid vehicles assessed achieve better than a 25% reduction in greenhouse gas (GHG) emissions, and just 3 exceed a 40% reduction, according to an evaluation by the Union of Concerned Scientists (UCS).1 Moreover, reductions in GHG emissions do not necessarily correlate with reductions in other toxic emissions. Like any engine output–improving technology, hybrid technology can boost both fuel efficiency and power—but the more you boost one, the less you can boost the other. That dichotomy spurred the UCS to develop its “hybrid scorecard,” which rates each hybrid according to how well it lives up to its promise of reducing air pollution.2 All the vehicles were from model year 2011 except for one, the 2012 Infiniti M Hybrid. First the UCS scored each hybrid on how much it reduced its GHG emissions relative to its conventional counterpart, on a scale of zero (least reduction) to 10 (greatest reduction). These scores reflect the percentage in fuel efficiency gain. For example, the Toyota Prius gets 50 mpg3 compared with 28 mpg for the comparable Toyota Matrix. This represents a 44.0% reduction in GHG emissions, earning the Prius a GHG score of 9.4. At the bottom of the scale, the 21-mpg hybrid VW Touareg reduces GHG emissions only 10% over the 19-mpg conventional Toureg, for a score of 0.0. With a 46% improvement, the luxury Lincoln MKZ Hybrid had the greatest reduction over its conventional counterpart. The UCS also scored hybrids for absolute emissions (rather than relative to the conventional model) of air pollutants including particulate matter, carbon monoxide, hydrocarbons, and nitrogen oxides. These scores, on a scale of zero (dirtiest) to 10 (cleanest), are based on California certifications for tailpipe emissions. As the scorecard showed, a vehicle that emits less heat-trapping gases may not necessarily emit less of other air pollutants. For example, the Mercedes Benz S400 Hybrid scored 9 on air pollution reduction, alongside the Prius and the Lincoln MKZ, but only 1.3 on GHG emissions. HYBRID SCORECARD: Top 10 Nonluxury Hybrids by Total Environmental Improvement Score “Hybrid technology doesn’t add additional challenges [to reducing exhaust pollutants] that can’t be addressed through design of the vehicle’s emission controls,” says Don Anair, senior vehicles analyst at the UCS. “Numerous manufacturers of hybrids are meeting the lowest emissions levels. Hybrid manufacturers who aren’t delivering the lowest smog-forming emissions have chosen not to do so.” Each vehicle’s air pollution and GHG scores were averaged into a total “environmental improvement score,” again with the MKZ and the Prius leading the pack, and the Touareg scraping bottom. The UCS also scored “hybrid value” (the cost of reducing GHG emissions in dollars per percent reduction) and “forced features” (options you must buy with the hybrid whether you want them or not). HYBRID SCORECARD: Top 10 Luxury Hybrids by Total Environmental Improvement Score Luke Tonachel, vehicles analyst with the Natural Resources Defense Council, compliments the scorecard for illustrating that hybrid technology is not automatically green. He says, “We should improve the efficiency of all vehicles, and [hybrid technology] is just one technology that can get us there if applied with that goal in mind.” Nonetheless, Jamie Kitman, the New York bureau chief for Automobile Magazine, questions the wisdom of emphasizing percentage improvement in gas mileage rather than absolute miles per gallon. At 21 mpg, the hybrid Cadillac Escalade 4WD represents a 29% improvement over the 15-mpg conventional model, saving nearly 2 gallons per 100 miles. But the hybrid Escalade is still a gas guzzler, and Kitman says he wishes people would see through the marketing that encourages them to buy SUVs and “crossovers” rather than ordinary cars, which are more efficient than either. Says Anair, “The scorecard shows that automakers can pair hybrid technology with advanced emission controls to help tackle climate change while reducing the health impacts from breathing polluted air.” However, he adds, alluding to the stark variation in how much hybrid technology boosted fuel efficiency, “Not all automakers are delivering on the full promise of this technology.”

The purpose of this research is to empirically reveal the effect of external technology R&D cooperation network diversity (ETRDCND) on the greenhouse gas (GHG) emission reduction and energy saving of small and medium-sized enterprises (SMEs). Besides this, this study aims at analyzing the roles of production time reduction and absorptive capacity in the relationship between SMEs’ ETRDCND and their GHG emission reduction and energy saving. GHG emission and energy usage have been playing a crucial role in aggravating global warming. Global warming results in big problems such as worldwide unusual weather and health disorders. SMEs play a substantial role in the industrial growth of the global economy, which increases GHG emission and energy consumption. By performing the ordinary least squares regression with the data of 3300 South Korean SMEs, this research reveals four points. First, ETRDCND positively influences SMEs’ GHG emission reduction and energy saving. Second, production time reduction perfectly mediates the relationship between SMEs’ ETRDCND and their GHG emission reduction and energy saving. Third, the mediating role of production time reduction in this relationship is moderated by SMEs’ absorptive capacity. Fourth, ETRDCND significantly influences SMEs’ GHG emission reduction and their energy saving only if SMEs possess their own absorptive capacity.

As part of the Net Zero Carbon Water Cycle Program (NZCWCP) for Victoria state in Australia, we have sought to understand the potential to reduce household energy consumption and related Greenhouse Gas (GHG) emissions by influencing water use. Digital metering data disaggregated into 57 million discrete water usage events across 105 households at a resolution of 10 millilitres at 10 second intervals from June 2017 to March 2020, from a previous Yarra Valley Water (Melbourne, Australia) study, was analysed, together with the dynamic relationship between the multiple energy sources (natural gas, grid electricity, solar) used to heat water for showers in each hour of the day. Water-related energy (WRE) use, including water desalination and treatment, pumping, heating, wastewater collection and treatment, comprised 12.6% of Australia’s primary energy use in 2019. Water heating (by natural gas and electricity) comprised the largest component of WRE use for across residential, commercial, and industrial sectors. Furthermore, 69% of Victoria’s total water usage was by residential customers in 2020-2021. WRE GHG emissions were around 3.8% of Victoria’s total GHG emissions in 2018. Showers (~50% of residential WRE), system losses (~27% of residential WRE), and clothes washers (~9% of residential WRE) are the three largest components of WRE consumption. The main objective of this work is the creation of industry-accessible tools to improve knowledge and management options from the understanding of reductions in cost and GHG emissions from household showering WRE use. Potential options considered, to reduce water and energy use, as well as associated GHG emissions and customer utility bills, include (a) behaviour management such as water and energy pricing to change time of use behaviours, and (b) the adoption of efficient shower head improvements. Shower WRE and GHG emissions were found able to be strongly impacted by small changes in daily routines. GHG emissions reduction from showering could be reduced up to 20 (in summer) - 22% (in winter) by shifting demand time of showering or replacing residential showerheads. Extrapolated to state and Australian scales, reductions in water usage could be up to 14 GL (Victoria) and 144 GL (Australia), and reductions in GHG emissions 1,600 ktCO2eq (Victoria) and 17,300 ktCO2eq (Australia). It provides fundamental new information which could inform a suite of new management options to impact water-related energy from showers, and related GHG emissions and customer water and energy cost.

Simple SummaryLivestock accounts for an estimated 80% of total agricultural greenhouse gas emissions, making abatement of greenhouse gas emissions from livestock a high-priority challenge facing animal nutritionists. Mitigating greenhouse gases in ruminants without reducing animal production is desirable both as a strategy to reduce global greenhouse gas emissions and as a way of improving dietary feed efficiency. The inclusion of feed additives in the diets of ruminants can reduce energy losses as methane, which typically reduces animal performance and contributes to greenhouse gas emissions. The present study evaluated the abatement potential of nine essential oil blends to mitigate greenhouse gas emissions. The inclusion of the blends resulted in a reduction in greenhouse gas emissions and in vitro apparent dry matter digestibility with higher values noted for the control treatment. A similar trend was noted for in vitro truly dry matter digestibility with higher values noted in the control treatment. The efficiency of microbial production was greater for the blends. The inclusion of the blends affected the total and molar proportion of volatile fatty acid concentrations. Overall, inclusion of the blends modified the rumen function resulting in improved efficiency of microbial production.The current study evaluated nine essential oil blends (EOBs) for their effects on ruminal in vitro dry matter digestibility (IVDMD), efficiency of microbial production, total short-chain fatty acid concentration (SCFA), total gas, and greenhouse gas (GHG) emissions using two dietary substrates (high forage and high concentrate). The study was arranged as a 2 × 2 × 9 + 1 factorial design to evaluate the effects of the nine EOBs on the two dietary substrates at two time points (6 and 24 h). The inclusion levels of the EOBs were 0 µL (control) and 100 µL with three laboratory replicates. Substrate × EOBs × time interactions were not significant (p > 0.05) for total gas and greenhouse gas emissions. The inclusion of EOBs in the diets resulted in a reduction (p < 0.001) in GHG emissions, except for EOB1 and EOB8 in the high concentrate diet at 6 h and for EOB8 in the high forage diet at 24 h of incubation. Diet type had no effect on apparent IVDMD (IVADMD) whereas the inclusion of EOBs reduced (p < 0.05) IVADMD with higher values noted for the control treatment. The efficiency of microbial production was greater (p < 0.001) for EOB treatments except for EOB1 inclusion in the high forage diet. The inclusion of EOBs affected (p < 0.001) the total and molar proportion of volatile fatty acid concentrations. Overall, the inclusion of the EOBs modified the rumen function resulting in improved efficiency of microbial production. Both the apparent and truly degraded DM was reduced in the EOB treatments. The inclusion of EOBs also resulted in reduced GHG emissions in both diets, except for EOB8 in the high forage diet which was slightly higher than the control treatment.