Abstract

Specific inhibitors of HIV-1 attachment, fusion and entry are one approach to a topical microbicide. We have been evaluating several such compounds (small molecules and peptides) targeting several different stages of the fusion process, for their abilities to prevent experimental infection of rhesus macaques with various SHIVs, after vaginal challenge. These results will be presented and discussed, in the context of developing a practical product for use in women and men.

Highlights

  • 2006 International Meeting of The Institute of Human Virology Meeting abstracts

  • A single PDF containing all abstracts in this Supplement is available here http://www.biomedcentral.com/content/pdf/1742-4690-3-S1-info.pdf

  • These results will be presented and discussed, in the context of developing a practical product for use in women and men

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Summary

Introduction

Entry inhibitors as topical microbicides to prevent HIV-1 sexual transmission Address: Professor of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, 10021, USA * Corresponding author from 2006 International Meeting of The Institute of Human Virology Baltimore, USA.

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