Abstract
Fæcal Escherichia coli from Bangalee patients with idiopathic diarrhœa were tested in the Chinese hamster ovary cell (C.H.O.) assay to detect production of thermolabile enterotoxin (L.T.). C.H.O.-positive E. coli produce both L.T. and a thermostable toxin (S.T.). C.H.O.-positive strains were found in 19.2% of all cases and in 70% of the most severely ill patients with non-vibrio cholera. E. coli which produce S.T. alone were identified in a third of the C.H.O.-negative cases. Enterotoxigenic E. coli were found in 55% of inpatients with idiopathic diarrhœa and, if an ætiological role is confirmed, may be one of the commonest causes of tropical diarrhœa.
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