Abstract
Zn, a biodegradable metal, exhibits immense capability as a bioresorbable implant material because of its remarkable biocompatibility and stronger corrosion resistance than Mg. Nonetheless, Zn's limited mechanical strength and hardness have significantly hindered its widespread implementation. This study aimed to strengthen the mechanical, degradation resistance, and biocompatibility of zinc composites by rolling them and investigating the impact of Mn content on the material properties of Zn composites. The prepared hot rolled Zn-1.5Mg-0.5HA(hydroxyapatite)-1.5Mn (ZMR2) sample shows enhanced Ultimate tensile strength (UTS 209 MPa) and hardness (103 HV). In a PBS solution, the degradation rates of the hot-rolled sample show a consistent reduction as the content of Mn increases, reaching a rate of 0.032 mm/year. Furthermore, excellent hemocompatibility was observed for both the cast and rolled specimens. However, the rolled ZMR2 sample exhibited the lowest value (4.5 %) among the two. The cultured MG63 cells demonstrated high viability when exposed to diluted extracts (25 % and 50 % extract) of the HR ZMR2 sample from Day 1 to Day 5. In both cases, the viability exceeded 80 %, indicating the absence of any potential cytotoxic effects.
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