Abstract
Candida, a yeast like ubiquitous fungus, is an endogenous species which produces commonest fungal infection; Candidiasis. Resistance to antifungal agents is an alarming sign for the emerging common nosocomial candidiasis. MATERIALS AND METHODS: Various types of specimens were collected from the clinically suspected cases of candidiasis. Isolation and characterization of candida sp. was done by standard procedures. Antifungal susceptibility was done by disc diffusion method. RESULT: The candida was isolated from various clinical specimens, vaginal swab (24.66%), skin scraping (13.33%) oral swabs (12.66%), ear swabs (11.33%), nail scraping (10%), and pus from diabetes foot ulcer and post-operative wound infection (8%), sputum (6%), urine (4.66%), stool (4%), blood (2.66%), and eye swabs (2.66%). Among different species of candida isolated C.albicans was the predominant species (79.33%) followed by C tropicalis (19.33%) and C.Guilliermondii (1.33%). Antifungal resistance of different species of candida was higher to fluconazole. The least resistance was seen with amphotericin- B (1.33%). CONCLUSION: The increased isolation of candida species and development of resistance to commonly used antifungal drugs requires careful interpretation and the in vitro susceptibility testing. This facilitates better patient care.
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