English

Abstract

Organophosphorus poisoning is the most common medico toxic emergency in India. Respiratory failure is the most common complication of OP compound leading to death. Early recognition and prompt ventilation may improve survival. The aim of the study was to correlate between the clinical score described by Peradenya Organophosphorus Poisoning (POP) scale, glasgow coma scale (GCS) and serum Pseudocholinesterase level at presentation, ventilator requirement and the outcome. This sectional study conducted at tertiary care centre, Nagpur from October 2011 to September 2013. 40 patients fulfilled the inclusion criteria and included in the study. Majority of patients were in younger age group with male preponderance. Agriculture is the most common occupation found in the patients in the study. Mortality was found in 17.5% patients and mortality was found to be higher in patients with severe grade of Paradeniya poisoning scale (score > or = 7) and severe grade of Glasgow coma scale (score < or = 8). Patients with normal cholinesterase levels showed significantly higher chances of survival as compared to those with less than 10% of the normal cholinesterase levels. Patients with severe grade of POP scale and GCS needed ventilatory support more frequently than patients with mild to moderate grade. Thus GCS, POP scale and Pseudocholinesterase levels can very well be used in assessing prognosis and mortality of patients of OP poisoning.