Abstract

Most developments in biotechnology during the last few decades focused on the potential applications of human health, vaccination being the most prominent invention to date. Disease prevention is the most convenient and highly effective approach to promoting human health and prolonging life. Vaccinations have prevented millions of deaths worldwide every year and diseases that used to kill, disable or debilitate millions of people are either gone or seen very rarely. Prevention is the first essential step that needs to be taken before a preventive medicine or vaccine is developed and public health pays a prominent role in this respect. This is, actually, what is happening currently with the Corona Virus (Covid-19) pandemic, although recently vaccines are being administered in different parts of the world. This paper reviews the traditional inoculation methods that were practiced in several societies around the world for the last several hundreds of years, before the advent of the modern vaccination techniques. The paper was compiled using literature review of various publications consultations of the customary laws, and interviews of knowledgeable people on the subject matter. The paper emphasizes how the traditional inoculation practices have laid down the foundation for the advent of the modern vaccination techniques. The principle of isolating infected people leading to the modern practice of quarantine. Key words: Inoculation, immunization, smallpox, traditional biotechnology, vaccination, vaccine, variolation.

Highlights

  • The term „Biotechnology‟ was first coined by a Hungarian engineer, Karl Ereky in 1919 who defined it as “all lines of work by which products are produced from raw materials with the aid of living things”

  • Traditional inoculation, which started to be practiced in China as of the 10th century, expanded throughout the world, employing different methods, until modern vaccination techniques were discovered by Edward Jenner, in 1798

  • Traditional inoculation was being practiced in different parts of the world for over 80 years to prevent death and debilitations that may have been caused by various diseases

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Summary

INTRODUCTION

The term „Biotechnology‟ was first coined by a Hungarian engineer, Karl Ereky in 1919 who defined it as “all lines of work by which products are produced from raw materials with the aid of living things”. Before the invention of antibiotics and vaccines, people in different parts of the world have been using various traditional practices of inoculation to prevent infectious diseases like smallpox, measles, etc., from spreading and killing people. All such processes, which are based on the natural capabilities of microorganisms, are commonly considered as old or traditional biotechnology. The paper shall, try to review the various traditional inoculation methods that were being practiced to prevent diseases in different parts of the world It will underscore how traditional societies have been handling infectious diseases; through the customary laws they have developed, by isolating infected persons and/or villages to prevent the spread of the disease to other villages and communities.

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