English

Abstract

AIM: To determine the prevalence of human immunodeficiency virus (HIV) infection among tuberculosis patients, to compare the clinical features of tuberculosis among HIV seropositive and seronegative patients, & to correlate the seropositive tuberculosis patients with the CD4 count. METHODS: This study was undertaken in Gandhi Medical College, Hamidia Hospital, Bhopal, in department of medicine during November 2008 to November 2009. A total of 150 radio logically and / or bacteriologically confirmed patients of tuberculosis were tested for HIV seroprevalence. RESULTS: Among 150 tuberculosis patients, thirteen (8.66%) were found to be HIV seropositive. Eleven (84.6%) were males and two (15.4%) were females. Among 13 HIV seropositive patients ten (76.92%) patients were in the age group of 21 - 40 years. Out of eleven HIV seropositive male patients five (45.45%) were labourers, four (36.36%) were truck drivers, Among HIV seropositive patients, eight (61.53 %) belonged to urban area & five (38.47%) were from rural areas. Eleven (84.6%) had contracted HIV infection through sexual contact, one was IV drug abuser, one was supposed to be infected by blood transfusion. five (38.46%) patients had disseminated/military tuberculosis (DTB/MTB), three (23.07%) patients had pulmonary tuberculosis, three (23.07%) had pleural effusion, two (15.38%) had neurotuberculosis. Ten (76.92%) seropositive patients had CD4 count <350.CONCLUSION: The trend of dual infection with HIV and tuberculosis in the area is rising. Atypical presentation, extrapulmonary and disseminated / military tuberculosis cases are more at CD4 < 350/ml