Abstract
Digitalizing Biology The living hydrogel optical fibers and polysaccharide-based photonic constructs fabricated by Rui L. Reis, Utkan Demirci, and co-workers in article number 2105361 are highly versatile and enable the screening of multiscale phenomena, from macro-level forces and shapes to nano-level biotarget detection. Living optical interactions further allow the direct quantification of dynamic cellular responses, ranging from metabolism to 3D proliferation and anti-cancer drug susceptibility—asking cells the right question.
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