Abstract

Bizarre parosteal osteochondromatous proliferation is a rare disease of the toes and fingers; occasionally occurring at other sites in the skeleton. However, it is highly uncommon in our population: this case is only the second reported at the National Cancer Institute of Colombia, and there are fewer than 100 cases mentioned in the English language literature. In most cases, the risk of over-diagnosis is high. Debate currently centers on whether this ailment is a true neoplasia, in light of what little is known of its chondrogenesis and ossification at the molecular level---greater knowledge of which could transform the diagnostic methodology and nomenclature, as well as therapeutic approaches for the osteoskeletal neoplasia and soft tissues. We present a case of Nora's disease, accompanied by a concise clinical summary with surgical pathology images and findings, along with a discussion on the current state of knowledge of this disease.

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