Abstract
Aroutine blood sample from a 60-year-old male was received with hemoglobin of 95 gm/L, total leucocyte count of 9.3 · 10/L, platelet count of 299 · 10/L and a normal differential leucocyte count. However, the peripheral blood film showed a cluster of cells appearing pleomorphic with a high nuclear-cytoplasmic ratio, a regular nuclear membrane with nuclear grooving, and abundant weakly basophilic cytoplasm identified as endothelial cells. Endothelial cells may appear in peripheral blood as extraneous cells. Other extraneous cells which can be seen include epithelial cells (either nucleated or non-nucleated) and subcutaneous fat cells. Clinical details of patient and morphological features help in their recognition. It is important to identify these extraneous cells, so that they are not misinterpreted as tumor cells (Fig. 1).
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