Abstract

Aim: The aim of this study was to classify the endosonographic features of gastrointestinal submucosal tumors.Methods: The endosonographic and clinicopathologic findings of 302 submucosal elevated lesions from 295 patients were compared.Results: Endoscopic ultrasound was able to clearly demonstrate the anatomical layer origin of the lesions. The internal echo patterns of the submucosal tumors could be categorized into seven types consisting of simple cystic (I), multicystic (II), solid cystic (III), hyperechoic (IV), isoechoic (V), hypoechoic (VI), and mixed solid (VII). Cysts, lymphangioma, and lipoma were characterized as type I, II, and IV images, respectively. Brunner’s gland hamartoma and heterotopic gastric mucosa showed various patterns of cystic and solid echoes (I–VII). Inflammatory fibroid polyps, granular cell tumors, and carcinoid tumors often manifested type VI images. Malignant tumors, particularly leiomyosarcoma, tended to show VII images.Conclusions: The endosonographic classification is considered to be important in the diagnosis of gastrointestinal submucosal elevated lesions.

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